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Then, seven machine learning approaches were used to establish the QSAR models for oral acute toxicity.
A sensitivity analysis, which included those participants without laboratory evidence of HHV-8 infection by either HHV-8 seropositivity, HHV-8 DNA detection from mucosal surfaces or blood, or biopsy proven KS, did not change the results of multivariate models for oral HHV-8 detection or viremia (data not shown).
Thus, we used the same strategy to assess the validity of models for oral drug absorption.
Given all of these facts, more examples of evaluated pediatric PBPK models for oral drugs are still in demand.
The study group by time interaction in the linear mixed models for oral contraceptives showed similar results to the negative binomial model (results not shown).
The model features a detailed representation of absorption models for oral glucose, subcutaneous insulin and glucagon, and an insulin receptor model relating pharmacokinetic properties to pharmacodynamic effects.
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The Decision Analytic Model for Oral Pre-cancerous Lesions.
This study established a basic in vitro single and mixed-species culture model for oral bacteria combining three complimentary methods.
4NQO-induced lesions appear to be a good model for oral cavity carcinogenesis [ 14].
A Golden Syrian hamster model for oral precancer was utilized in this study [ 30].
There were six variables in the final model for oral cancer in women.
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