Sentence examples for models for mm from inspiring English sources

Appropriate use and improvement of animal models for MM will undoubtedly help to clarify the pathological mechanisms and benefit the development of treatment approaches (Table 1).

The development of successful animal models for MM also relies on the choice of the biomarkers used to track the disease course and to identify tumor cells in mouse tissues [ 27- 32].

Although genetically engineered mouse models for MM have been developed, at present no model is available that reliably mimics the human disease and is suitable for studying mechanisms of therapeutic obstacles including cell death resistance.

Currently available murine models for MM include immunocompetent mice, such as the 5TMM series [ 12, 13] and genetic models of MM [ 14, 15], or immunocompromised mice, namely, NOD/SCID [ 16], SCID-hu [ 17, 18], and NOG [ 19, 20].

Currently available murine models for MM include immunocompetent mice, such as the 5TMM series [ 48, 49] and genetic models of MM [ 50- 52], or immunocompromised mice, namely NOD/SCID [ 13- 23], SCID-hu [ 53- 56], and NOG [ 24, 25, 38, 57].

We develop a mixed integer programming model for MM-TOPTW based on the standard TOPTW model with additional considerations of transportation mode choices, including transportation cost and transportation time.

For our studies, we exploited our SCID-rab and SCID-hu mouse models for primary MM [15], [34] [37].

Despite much effort, the development of mouse models for human MM remains a challenge [ 35].

It is also different from in vivo models for primary MM that use fetal bone, such as the SCID-hu model [ 11, 12], or that lack human hematopoiesis, such as the calcium phosphate-based scaffold [ 16].

We used Hg cells, along with the SCID-rab and SCID-hu model systems for MM [34], [35], to characterize the effects of PTH on bone metabolism and on myeloma growth in myelomatous bone and to shed light on the molecular mechanisms of PTH.

Furthermore, two separate predictive models for 37.5-mm and 9.5 to 25-mm NMAS mixes were successfully developed based on regression analyses.