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That makes experiments with them easier to reproduce and control, but it has also raised serious concerns about whether or not they're realistic models for humans.
Adipocyte numbers were increased by feed withdrawal (FW) regimens in cattle; thus, the effect of FW regimens was studied in male Wistar and fa/fa obese rats, as models for humans, in 2 completely randomized design experiments to abate lipodystrophy and progression of metabolic syndrome symptoms.
The results lay the foundation for future gastrointestinal research applying guinea pigs as models for humans.
Therefore, rodents frequently serve as models for humans in ecotoxicology [ 4].
These facts alone should give us pause when considering using animals as models for humans.
Recommendation (8) REAPPRAISE the validity of the hypothesis that animals make reliable models for humans and that they possess predictive value.
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Marvelling at the symptomatic parallels between his own patients and Lathrop's mice, Loeb asserted that rodents might serve well as models for human disease.
Cynomolgus macaques are relevant models for human diseases and transplantation.
Rhesus monkeys are relevant models for human diseases and transplantation.
I ended up working on different animal models for human epilepsy using slices of brain tissue.
"It is one of the few good models for human brain evolution," he says.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com