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These estimates of the in vivo mechanical environments may be used to design in vitro models for elucidating the cellular and molecular mechanisms of bone adaptation and pathological bone loss.
Amphibians are attractive experimental models for elucidating the mechanisms underlying animal development.
During the last decade, interest in using network models for elucidating mechanisms of disease has constantly increased [ 1].
Exocrine gland cells have provided the most important models for elucidating the mechanisms underlying hormone- or neurotransmitter-evoked intracellular Ca2+ release.
Finally, they exemplify the power of conditional mouse models for elucidating how specific molecular mechanisms give rise to the complexity of human cancer.
Therefore, being relatively resistant to arginine deprivation, three glioblastoma cell lines served in our hands as useful and informative models for elucidating and dissecting possible specific effects of arginine withdrawal relevant to metastatic potential of malignant cells.
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Background: The skeletal neuromuscular junction is a useful model for elucidating mechanisms that regulate synaptogenesis.
These mice may provide useful animal model for elucidating the mechanisms of lens development, and etiology of microphthalmia.
Antibodies may be regarded as the products of a protein engineering system developed by nature for generating a virtually unlimited repertoire of complementary molecular surfaces and, as such, constitute an excellent model for elucidating the principles governing macromolecular recognition.
In addition to being an important pathogen in livestock, PrV is being used increasingly as a model for elucidating the basic mechanisms of herpesvirus infection in cell culture and in the animal.
Thus MRL-lpr/lpr mice display a selective defect in MPS Fc receptor function and may provide a valuable model for elucidating the etiology and importance of MPS dysfunction in immune complex deposition disease.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com