Lacroix, M. & Leclercq, G. Relevance of breast cancer cell lines as models for breast tumours: an update.
A renowned scientist at the peak of his career developing animal models for breast cancer, his humanistic qualities will be forever remembered.
The intention of this review is to provide a succinct overview about the availability and relevance of the major categories of mouse models for breast cancer.
In this review, we discuss the relative relevance of the most commonly used transgenic mouse models for breast cancer prevention studies, and provide examples of how these transgenic models can be used to conduct cancer prevention research.
In this work, we report investigations of the innate immune response to the oncolytic poliovirus recombinant, PVSRIPO, in two mouse xenotransplantation models for breast and prostate cancer.
In summary, the generation of animal models for breast cancer is becoming increasingly complex.
Many observations in mouse models for breast cancer support this paradigm [ 36].
For example, there are over 60 published predictive models for breast cancer.
Among the mouse models for breast cancer, xenografts still play the dominant role in preclinical trials.
Application of the reporter gene approach to animal models for breast cancer is discussed.
No prediction models for breast cancer have achieved this level of discrimination to date.
