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Fortunately, gnotobiotic animal models fashioned using human microbiota and diets representative of the very population(s) targeted for disease treatment and prevention are a source of new microbial and metabolic biomarkers that could be used to judge the safety and efficacy of these envisioned microbiota-targeted therapeutic interventions.
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MR data was modeled in a similar fashion using the same single tissue compartment model in PMOD in order to provide relative measurements of MR-based perfusion that are independent of the effects of PET detector dead time.
We then compared successive models in a hierarchical fashion, using nested F-tests to determine if the most recently added set of predictors added explanatory power to the existing model.
Secondary outcomes will be analysed in a similar fashion using regression models with link functions and error terms appropriate to the distribution of the outcome of interest.
The network model was constructed in a modular fashion using a "building block" framework in which the responses to several key types of stressors were modeled (see Figure 1).
National and supranational trends were calculated from these in a hierarchical fashion using a model (applied in the software package TRIM) in a way that allows for missing observations [16], [17].
For comparison, models were built in a similar fashion using only the clinical features and separately using all study subjects (rather than the 7 3 training:testing split).
Models were constructed in a staged fashion using HIV status, demographics (age, sex, and race), lifestyle factors, and MRI AT depots as predictor variables.
Differential gene expression analyses between both cell models were performed in a pairwise fashion using BRB-ArrayTools (developed by Dr. Richard Simon and the BRB-ArrayTools Development Team).
In a similar fashion, using an AR model, PSD results are obtained by employing different schemes under a real noisy environment of a multitalker babble noise (multiple background competing speakers) taken from the Noisex92 database [24].
These models can be represented in a compact fashion using Kronecker algebra.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com