Sentence examples for models expression of from inspiring English sources

Furthermore, in transgenic mouse models, expression of activated Pak1 in breast epithelia is oncogenic, consistent with a functional role of Pak1 in tumor progression [3].

Conversely, in animal models, expression of FABP4 in adipocytes has been associated with overall insulin resistance (11– 11).

In tumour allograft models, expression of a constitutively active STAT3 leads to increased VEGF expression and increased vasculogenesis.

Despite the elevated levels of ER in both resistant models, expression of classic ER response genes (for example PGR and TFF1) were substantially reduced.

Within cell and fly models, expression of this deletion mutant increased LC3-II levels, caused an accumulation of autophagosomes, and decreased the formation of MVBs.

In these mouse models, expression of dominant negative Lef1 results in de novo formation of SGs and enlargement of existing glands.

In the BALF model, expression of the ClpX protein increased (but was not significantly over-expressed (p > 0.05) in the macrophage model).

In our model, expression of a dual drug resistance marker, driven by an NF-κB-dependent minimal promoter, provides a selective and highly sensitive scheme with a quantitative readout to detect biochemical agents with pro-or anti-inflammatory properties.

These results indicate that, in this transgenic model, expression of CC10, which is widely used to determine whether lung tumors arise from Clara cells, was reduced and subsequently lost during Clara cell tumor progression.

There was negligible gene expression from pEC-XT99A without IPTG when we tested the model expression of the gfpuv gene, whereas the expression of the gfpuv gene from pEKEx3 without IPTG addition was 20 30% of the maximum after IPTG induction (data not shown).

In this model, expression of TLX1 was placed under the control of the Lck-promoter in order to limit conditional expression to T-lineage cells.