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In summary, RGC axons in a variety of genetic mice models display distinct and independent phenotypes on the crossing or uncrossing at the chiasm.
However, the two models display distinct synaptic and behavioral alterations and it would thus be interesting in future studies to examine the consequences of mutations preventing the expression of both proteins.
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The two models displayed distinct transcriptional profiles before and after treatment.
However, these are expensive, time consuming and, as with most animal models of human disease, display distinct differences from the typical clinical presentation of alcoholics.
Additionally, it tends to model two independent decisions that may display distinct effects on the different dependent variables being considered.
Using the adhesion protein fibronectin, whose multiple repeats essentially display distinct molecular recognition motifs, we derived a computational model to explain how minimalistic designs of repeats translate into the mechanical characteristics of their fibrillar assemblies.
Depending on the micro-environment, macrophages display distinct activation (also called polarization) states.
Normal fibroblasts and cancer-associated fibroblasts (CAFs) have been shown to display distinct gene expression signatures.
Patients with similar clinical presentations often display distinct tumor responses to standard of care (SOC) therapies.
Metastatic cancer cells display distinct genomic and epigenomic profiles and almost universally an aggressive pathophysiology.
Pluripotent hESCs also display distinct epigenetic properties.
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