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This work provides a comprehensive review of the state of the art with respect to multiscale computer models designed to provide a mechanistic prediction of local and systemic drug exposure following inhalation.
Here we briefly review the progress achieved in the field and focus on experimental systems in animal models designed to provide a 'proof of concept' towards the onset of clinical trials.
In particular, the dimensionality of the system is often reduced, especially in models designed to provide a qualitative description of frictional properties of elastic materials, e.g. the spring-block model.
Precision agriculture, a collection of data collection, analysis and prediction technologies that looks like something out of Google, not John Deere, describes a group of technologies designed to collect and analyze detailed information about growing and crop conditions that feed complex models designed to provide actionable recommendations to improve yields and reduce costs.
Jessica Bolker has distinguished exemplary and surrogate modes of representation (Bolker 2009), where the former serve basic research by exemplifying a larger group and the latter correspond to models designed to provide indirect experimental access to otherwise inaccessible phenomena, such as mouse models of human psychological disorders (e.g., schizophrenia).
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This paper represents an on-going research and concerns the development of an unified formal modeling framework designed to provide for model sharing, reusability and integration of simulation and optimization methods to allow decision-makers to master the dynamics of complex discrete systems.
The Food and Drug Administration, which licences medicines in the US, believes the Ebola drug trials should be set up in west Africa on the "gold standard" model designed to provide a conclusive answer as to whether they have an effect.
We examine the geometry of diffusion flames generated by the burning of a heterogeneous solid propellant, using a simple model designed to provide qualitative insights.
The Perioperative Surgical Home is a novel care model designed to provide patient-centered, high-quality surgical care.
Factors such as sample volume, sample pre-treatment and the time and temperature of sample equilibration have been included in an optimisation model designed to provide maximum detector response for acetic, propionic, iso- and n-butyric and iso- and n-valeric acids in the concentration range 0 1000 mg/l.
Organic loading rate, variation in organic loading rate, and the presence of filamentous microorganisms in the activated sludge system, used as a feed source for the digester, have been selected as the inputs of a knowledge-based model designed to provide as output the risk of foaming in an anaerobic digester.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com