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The other model parameter is θ s t ; j k, which models dependency between variable X s and variable X t when they take values j and k, respectively.
These profiles and their biological interpretation are as follows: (i) the sum of mRNA expression levels, which models cooperation, (ii) the difference between mRNA expression levels models competition, (iii) the maximum mRNA expression level models redundancy, and (iv) the minimum mRNA expression level models dependency between a pair of genes.
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This article can thus be considered as an extension of [3], modeling dependencies between-sources through generalizing the prior to multivariate GMM.
For the first phase, we learn the full structure of a Bayesian network (BN) that models dependencies between the discrete target labels of the HTS assays.
We consider (i) a standard log-fold change (LFC) analysis that does not integrate dependencies between adjacent genes on DNA; (ii) a two-state HMM that models dependencies between adjacent genes on DNA; and (iii) an extension of the two-state HMM to an HMM with scaled transition matrices (SHMM) that specifically models directly adjacent genes on DNA that are in head head orientation to each other.
This paper present a technique to model dependency between variables in view of the construction of bivariate distributions based on that dependency structure.
In DRABAL, we incorporate structure learning of a Bayesian network (BN) as a step to model dependency between the HTS assays.
Here we present DRABAL, a novel MLC solution that incorporates structure learning of a Bayesian network as a step to model dependency between the HTS assays.
The authors model dependency between multiple events of a patient by frailty: doctor visits during the subject's time in study.
The current software can model dependency between the processes using either the current underlying longitudinal value (W2 i (t)= m i (t)), the rate of growth (W2 i (t)=d m i (t)/d t) or both.
In the current context, we choose the "working independence" assumption for modeling dependencies between probes [ 8, 9]., to avoid making any assumptions on dependence structures.
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