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The drug release data were fitted with various kinetic models, data not shown.
Overall, no differences were noted compared to the results from the full models (data not shown).
Similar results were obtained for MDA-MB 231 derived models (data not shown).
However, no parallel increase in respiratory complex activity was detected using biochemical techniques in neuronal models (data not shown).
There was no significant effect of lead or lag scale (±1 5 days) on regression models (data not shown).
After adjustment of the maximum conductance of IKr (GKr,max) there were only minor differences in the shape of IKr when comparing the two models (data not shown).
The 17 gene/probe model correctly classified 5 15 more patients into their known category (PSA controls or SYS cases) compared to the other models (data not shown).
Similarly, no associations between genotypes and serum insulin release or insulin sensitivity were found when applying recessive and dominant models (data not shown).
In the duodenum inclusions were observed in the ganglion cells of the myenteric and submucosal plexi and the interstitial connective tissue in both mouse models (data not shown).
For these three genes the multi-marker models indicated a similar modification of GMT, but with reduced significance compared to single SNP models (data not shown).
Conditional and unconditional models (data not shown) produced similar results.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com