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In addition, we considered regression models containing the covariate age, either by itself or in combination with storage energy or energy density, because age has been previously suggested to influence reproductive success in polar bears21,49.
We chose to limit the comparison of models containing the same four covariates without interactions.
First, models containing the ACE and ADE components were fitted separately.
No models containing the interaction between temperature and length ranked among the top models.
Predictions from this approach were compared with the predictions from logistic regression models containing the same set of variables.
There was no statistical evidence of sex differences in these associations (p values for sex interaction.22 and.80 in models containing the main effects).
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These channel models contain the class of channel models studied in [8] as a special case.
Three of the four final multiple regression models contained the same variables although the parameter estimates varied slightly.
The models contained the CURB65 covariates alone, jointly with proADM, and jointly with all remaining biomarkers.
Both models contained the respective dichotomised EQ-5D-3L item as dependent variable.
These models contain the scope of integration of genomics, transcriptomics, proteomics, metabolomics and phenomics data.
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