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Hippocampal size declines with both age and Alzheimer's disease severity, and the models clearly demonstrate these effects.
Pre-clinical models clearly demonstrate that chemotherapy can synergize with immunotherapy, raising the question how the immune system can be mobilized to generate anti-tumor immune responses in the context of chemotherapy.
Genetically manipulated mice models clearly demonstrate that ER stress and UPR influence insulin signaling and glucose homeostasis (Table 1, Figure 1(a)).
Although these models clearly demonstrate the critical role for cathelicidin in host defence against infection, it remains unclear to what extent this is due to microbicidal or modulatory properties of the peptide.
A large number of studies on rodent models clearly demonstrate that USVs are a sensitive (and almost unique) and reliable marker to detect short-term neurotoxic effects of developmental exposure to environmental contaminants [ 53- 55].
The monitoring and private well models clearly demonstrate a difference in concentrations based on depth, so well depth could quantify this more explicitly as opposed to categorically as done by this study.
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The evaluation of predictions by existing models clearly demonstrates the need for improvement.
Owing to the high correlation with 2006-RD2T (Table 8), ANN downscaled the rainfall in all models, clearly demonstrating a good pattern-correlation.
Most importantly, their application in treating acute and long term chronic MI in rat models clearly demonstrates the significant therapeutic potential of these gels in the long-term (12 weeks post MI).
Experiments performed both in in vitro as well as in in vivo models clearly demonstrated that they could not determine de per si anaplastic thyroid transformation, and other genes ought to be involved in that mechanism (Wynford-Thomas, 1997).
In conclusion, our analysis of experimental models clearly demonstrates that SYN accumulation causes both a shift in the EEG spectrum toward slower brain oscillations as well as aberrant network excitability.
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