Sentence examples for models at young from inspiring English sources

High fat diet (45% calorie from fat) and the leptin receptor mutant db/db obesity models at young and older age were used for comparison.

Thus far, all cancer vaccines used in clinical trials have only been tested in preclinical models at young age.

Although IL-2 and IFN γ levels were significantly higher in the Mage-b than in the control groups for both models (at young age), the control groups showed immune responses to Mage-b as well.

The effect of pcDNA-3.1 and Listeria-based vaccines, expressing TAA Mage-b, on Mage-b-specific immune responses was tested in spleens and draining lymph nodes (LNs) of mild (4TO7cg) and aggressive (4T1) syngeneic metastatic mouse breast tumour models at young (3 months) and old (20 months) age.

Similar results were obtained with the 4T1 model but Mage-b-specific immune responses were weaker in the 4T1 than in the 4TO7cg model at young age.

A similar effect of anti-OX40 was observed in a syngeneic prostate cancer model at young and old age (Sharma et al, 2006).

A significant increase was observed in the number of IFN γ-producing Mage-b-specific CD8 T cells after Mage-b vaccination in the 4T1 model at young but not old age.

Here, we studied the semi-therapeutic effects of three Listeriaat immunisations (one before and two after tumour development) on MDSC in blood and tumours of the 4T1 model at young (3 months) and old (18 months) age.

They found that adding anti-OX40 or anti-4-1BB mAb to a DC-based vaccine, resulted in vigorous anti-tumour responses in a syngeneic TRAMP-C2 model at young and old age, whereas without anti-OX40 or anti-4-1BB, protection was significantly better in young than in old mice (Sharma et al, 2006).

The United Nations UN DESA/Population Divisionn 1982) construct life tables for developing countries by fitting the Gompertz-Makeham model at younger ages and closing at age 85+.

One commercial for its lower-priced model aimed at young people is a comical spot showing a couple dropping off a 2-year-old after a horrendous baby-sitting experience.