We will use a lattice-theoretic approach [ 18], which includes classical constraint-based models at steady-state as a special case, but which is much more general.
A singular value decomposition (SVD) of the plasma model at steady state is carried out to decouple the system and identify the most relevant control channels.
An effective hydrogen diffusion coefficient based on the volume fraction of solid only could be deduced from the results of the numerical model at steady state.
In Fig. 4, we show the mixing ratios of this nominal model at steady state.
The network was modeled at steady state based on the framework reported by Goldbeter and Khoshland [59].
Equations 1 3 and the PK model at steady state are multiplicative, except when different versions of Equation 2 are added to sum contributions from indoor and outdoor air.
Rate-constants (α i, β i and γ r) are parameters that are computed so that the flux in the model at steady state is equal to the operating flux at the operating point for the metabolites.
In the limit of zero oxygen (i.e. eliminating every species containing oxygen), we have: (25) Therefore, the maximum theoretical concentration of HIF1α in the model at steady state (qmax) is determined by the production and turnover rates of HIF1α.
