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To further elucidate the WNV-S100B neurotoxic pathway, in vivo studies using mouse models are warranted.
Obviously, most of the widely used cachexia and sarcopenia animal models have limitations in reproducibility of the condition and novel models are warranted in this context.
Further studies in animal models are warranted to investigate the relative contributions of renalase secreted from the kidney and the heart to the inhibition of cardiac hypertrophy.
Hence, experimental exacerbation models are warranted.
Animal models are warranted to meet the needs mentioned above.
Future studies that extend the current in vitro observations into in vivo models are warranted.
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Moreover, incomplete lethality in the model allowed for survival in control groups not receiving vaccination, thereby complicating the vaccine-specific effect on survival.15 Further testing in pre-clinical models is warranted.
The conclusions are that a more explicit operationalization of GFE is needed for increased use, and that systematic and empirical study comparing GFE with other evaluation models is warranted.
Intensive training of interviewers to standardize instrument administration as well as assessment for interviewer error and its correction, using appropriate statistical models, such as multilevel models, is warranted.
Given the need for increasing the efficiency, speed, and quality of molecular imaging in pre-clinical research, this application of automated quantitative imaging studies for small animal models is warranted.
We believe that further research on the underlying algorithms for the model presented here and similar models is warranted.
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