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Although a number of mouse strains develop obesity and obesity-associated insulin resistance under certain conditions [ 25, 26] most of these models are resistant to atherosclerosis [ 27].
None of the models are resistant to whitewashing attacks.
Traditional models are resistant to open innovation.
Thus, our proposed models are resistant to model over-fitting and weak signal to noise ratio during the learning phase and can avoid the vanishing gradient problem in this scenario.
Similar(56)
Thus, we limit our scope to those three attacks to keep the comparisons concise in Table 2. CertainTrust model is resistant to sybil and FPA attacks, while EigenTrust is resistant to sybil and Buchegger's model and socialREGRET are resistant to FPA attacks only.
However, the impairment of social behaviors in this model is resistant to both clozapine and haloperidol treatment.
MK2-deficient hearts subjected to 30 min ischemia followed by 2 hours of reperfusion in the Langendorff model were resistant to myocardial IRI and also showed a diminished number of apoptotic cardiomyocytes [ 56].
AhR activation has been exhaustively studied by evaluating dioxin-induced CYP1A induction, tumor promotion in constitutively active AhR models and AhR polymorphism rat models that are resistant toward dioxin (Viluksela et al. 1997, 2000; Pohjanvirta et al. 1999; Moennikes et al. 2004; Brunnberg et al. 2006).
Gefitinib is active also in breast cancer cell models which are resistant to endocrine therapy (Nicholson et al, 2002; Knowlden et al, 2003; Shou et al, 2004).
In addition, ixabepilone is active in preclinical tumor models that are resistant to paclitaxel due to mutations in β-tubulin [ 22, 43].
Additionally, it has been shown that such agents are exceedingly effective at blocking the proliferation of models that are resistant to endocrine therapy, probably because CDK4/6 is downstream of multiple pathways (for example, Her2 and PI3K) that are implicated in the bypass of endocrine therapy [ 70, 72, 73].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com