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For these analyses, animal models are instrumental to study alterations at the molecular and cellular level.
True 3D geological models are instrumental in addressing practical geology problems.
Posture control models are instrumental to interpret experimental data and test hypotheses.
Animal models are instrumental in understanding disease pathophysiology and mechanisms of therapy action and resistance in vivo.
Mathematical models are instrumental tools to predict gas (O2 and CO2) evolution in headspaces of modified atmosphere packaging (MAP).
Numerical models are instrumental to more effective flood forecasting and managementservices though they suffer from numerous uncertaintysources.
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Generating human skeletal muscle models is instrumental for investigating muscle pathology and therapy.
Mouse models were instrumental in defining the signaling pathways defective in NTDs, including the planar cell polarity (PCP), also called noncanonical Frizzled/Disheveled pathway.
Over the years, the use of NHP models was instrumental for generating this paradigm of HIV infection, in which inflammation is at the core of HIV pathogenesis [ 2, 7, 8– 27].
Although toxic models were instrumental in the understanding of some of the mechanisms involved in cell death (DiFiglia, 1990), they were limited because it was not possible to study the progression of the disease or to replicate the widespread neuropathology observed in the human condition.
The parsimony of the mathematical model is instrumental in minimizing the number of bifurcation parameters.
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