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Most BA models are induced to simulate the pathological conditions without discriminating secondary or primary causes [ 17].
Most of established animal models are induced by chemical compounds (such as streptozocin, STZ) or genetically modification [ 3– 5].
Assuming DTIC, linear models are induced on the increments of the observed data as well: (6) where.
These models are induced by a wide variety of methods that include repeated muscle insults, depletion of biogenic amines, and stress.
Furthermore, a variety of responses regarding food intake and water consumption in constipation models are induced by several herbal medicines and foods.
Both the AIA and mBSA/IL-1 models are induced using an intra-articular injection resulting in monoarticular arthritis in the injected joint.
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Limbal stem cell deficiency models were induced by alkaline injury, and the TEC was implanted for 8 weeks.
Type 2 diabetic rat models were induced by means of a high fat diet and intraperitoneal injection with streptozotocin.
Gene deletion in both models was induced in adult animals, thereby minimizing developmental influences.
In another recent study by Kjaer et al. [13], genotype-phenotype correlation models were induced for all clinically used NRTIs (except for ddC), by use of artificial neural networks (ANN).
Eighteen septic shock swine models were induced.
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