Sentence examples for models and trials from inspiring English sources
Given emerging evidence from preclinical models and trials presented in abstract form, there are also indications that obatoclax may be more effective when used in combination with other anticancer therapeutics.
The next step is to find out whether these potential findings will bear out when tested in human models and trials; but which of the literally thousands of potential findings get worked up and moved forward along the translational cycle?
Drugs that induce DNA-strand breaks, such as cis-platinum, show increased sensitivity in pre-clinical models, and trials are now underway to study cis-platinum and PARP1 inhibitors in women with breast cancer and a BRCA mutation.
For this reason, we have confidence that the proposed method is robust within ±10% noise ratio (more complicated models and trials on P2 can be found in part I of additional file 1). Figure 1 shows the responses of one trial.
Professional experience in clinical care, and particularly care of children, predicted favorable attitudes toward nonanimal preclinical models and trial initiation when sub-optimal treatments were available.
It is generally accepted that targeted cancer drugs cannot be used on a 'one size fits all' model and trials need to reflect the original fundamental biology.
The first controller is designed based on the information obtained from the bifurcation analysis results of the aircraft model and trial and error simulation experiments.
The impact of both the model and trial assumptions may be equally large.
In most training programs, professionalism and collaboration are part of an implicit, ad hoc curriculum largely consisting of role modeling and trial and error.
We define the residuals Z as the paired difference between the two sets of results (model and trial): Z = Y − X, i = 1, 2,…, n.
This having been said, it follows that, were a future clinical/economic trial to reproduce the parameter values employed in this model, then a screening programme consistent with both model and trial would itself be cost effective.
