For example, despite data that indicate the positive effects of teachers and schools on students' learning, current curricular innovations designed to increase students' academic outcomes are typically based on atheoretical models and lack substantial empirical support.
In the present study, we assessed the anti-neoplastic activity of targeting cMET with INC280 in pancreatic cancer models and found substantial in vitro inhibition of HGF-induced cancer cell motility and –signaling, as well as reversal of resistance-mediating properties.
Animal model studies and substantial clinical data suggest that blood-brain barrier breakdown frequently follows head trauma [ 24].
Part of the reason for this is that, while education is becoming increasingly attractive to investors, there's still a lot of uncertainty in the space and companies with viable business models, revenue growth and substantial user bases remain in the minority.
"The new rules will require changes to firms' business models and will bring substantial long-term benefits to the competitiveness of the U.K. financial services sector," the regulatory agency said in a statement.
There is an assumption in the literature that the UML is the de facto standard, and that use of design models has had a profound and substantial effect on how software is designed by virtue of models giving the ability to do model-checking, code generation, or automated test generation.
The dials on the 17-year old Model One are solid and substantial.
This careful study with a non-model organism adds new and substantial insight into the function of ABC transporters in insects and how insects deal with noxious compounds produced by plants they feed on.
However, evidence for the association of fast ripples with epileptic foci depends on animal models and human cases with substantial lesions in the form of hippocampal sclerosis, which suggests that neuronal loss may be required for fast ripples.
Models wore substantial underwear (and nothing else) at Bottega Veneta, Helmut Lang and John Galliano.
