Sentence examples for models and safety from inspiring English sources

In this paper, we show that this knowledge could be exploited in the context of an on-line hazard-directed monitoring scheme in which a suitable specification derived from design models and safety analyses forms a reference monitoring model.

These disappointing results pointed to the urgency in understanding the detailed biological mechanisms responsible for microbicide toxicity and the necessity to develop new in vitro models and safety biomarkers, in order to improve the prediction of clinical outcomes in large-scale efficacy trials in the future.

This has consequences for battery modelling and safety.

This BN approach is a particularly powerful approach when combined with material modelling and safety by design paradigms.

Pulmonary absorption was studied in a rat model, and safety of the formulations was evaluated by measuring cytotoxicity in Calu‐3 cells and assessing injury markers in bronchoalveolar lavage (BAL) fluid.

Then, in planning phase, a general assessment framework that integrates mobility simulation and safety simulation models needs to be used (Fig. 3).

After preclinical trials in animal models, efficacy and safety evaluation of the most promising vaccine candidates described has to be performed in humans.

Discussion: To maximize marine and offshore safety, risks need to be modeled and safety-based decisions need to be made in a logical and confident way.

Prior to moving into patients, stringent pre-clinical studies are required that have at least some rationale and efficacy in animal models and good safety profiles.

Proof of Principle studies are an early stage of clinical drug development when a compound has shown potential in animal models and early safety testing.

In contrast, antibodies like mouse anti-mouse TNF-alpha are expected to avoid host responses and are desirable for efficacy assessments in mouse disease models and early safety studies.