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Ligands for PPARγ suppress breast carcinogenesis in experimental models and induce differentiation of human liposarcoma cells.
Phthalates can activate the three peroxisome proliferator activated receptor (PPAR) isotypes on cellular models and induce peroxisome proliferation in rodents.
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In general, animal glaucoma models are classified into two categories: natural-occurring models and induced models.
We have recently reported that dantrolene which targets ryanodine receptors can prevent the death of neurons and β cells in Wolfram syndrome using mouse models and induced pluripotent stem cell (iPSC) models of the disease [ 19].
In contrast to intact A β, a synthetic peptide corresponding to isoAsp7-A β(1 42) causes cerebral amyloidosis in AD animal models and induces neuronal cell death by apoptosis.
It can be concluded that time delay may destabilize the equilibrium of that model and induce periodic oscillations.
Both treatments stabilise Hif-α in the zebrafish model and induce downstream target gene expression (e.g. transcription of phd3; Elks et al., 2011; Kajimura et al., 2006).
The total stress spectrum were calculated by summing stress spectrum induced by wind load from the ANN model and induced by inertia load from motion analysis based on linear wave theory.
It is possible to compensate the deficit in murine Dyrk1a heterozygote by the addition of one copy of human DYRK1A; the correction operates also on the phenotypes seen in the YACtg152F7 model and induced by the overexpression.
We used the established murine model and induced AA-amyloidosis in NMRI mice by intravenous injections of purified amyloid fibrils ('amyloid enhancing factor') combined with inflammatory challenge (silver nitrate subcutaneously).
One of the advanced force fields is AMOEBA as it employs the multipolar electrostatic model and induced atomic polarization.
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