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Systemic, enzyme-mediated depletion of L-arg has been investigated in mouse models and human trials.
Natural orifice transluminal endoscopic surgery (NOTES) has been established in animal models and human studies.
More generally, our approach illustrated a potential translational research bridging animal models and human studies.
Encapsulation of islet cell grafts has been successfully reported both in animal models and human subjects[19, 20].
Further studies are needed to validate whether such combination antimicrobial approaches are useful in animal models and human infection".
Research is conducted using in vitro methods, animal models and human volunteers.
This approach of selectively inducing apoptosis in tumor cells has proven effective in animal models and human trials.
IL-23 is a key pro-inflammatory cytokine driving autoimmunity in animal models and human diseases.
These inconsistencies between animal models and human diseases intensify the dispute on oncogenic or anti-neoplastic properties of BCL11B.
Several factors may contribute to the differences in phenotype between the animal models, and human MODY/RCAD patients.
On ethical grounds any such evaluation should begin with an in vitro screening before using animal models and human studies.
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