Sentence examples for models and genetically from inspiring English sources

The agents are being tested in preclinical cancer models, including tumor transplant models and genetically engineered models of spontaneous cancer.

The Diabetic Mouse Breeding sub-core maintains and interbreeds key strains of mutant and/or genetically modified mice and distributes them to diabetes researchers within the DRC, including novel humanized models and genetically modified NOD strains generated by the Molecular and Gene Targeting sub-cores.

Here, we describe a selection of cellular experimental systems, tumor transplantation mouse models and genetically engineered mouse models that are used for monitoring specific processes involved in metastasis, such as cell migration and invasion, and for investigating the full metastatic process.

We have established genetically defined human cell-based models and genetically engineered murine models for the pediatric skeletal muscle cancer known as rhabdomyosarcoma.

Using cell line models and genetically manipulated mice, we have demonstrated that DGKα and ζ isoforms play critical roles in: T cell development, activation, and anergy by regulating T cell receptor signaling; FcεRI signaling and mast cell function; and Toll-like receptor signaling and innate immune responses.

However, little is known about the genetic basis of bacterial OM largely due to practical difficulties in conducting research in ear infection models and genetically manipulating clinical isolates.

Moreover, the ability to extend these findings in vivo using the CAM cancer model and genetically tractable cell lines could help identify important signaling programs that operate in live animals.

Amplified fragment length polymorphism is a powerful and robust molecular marker technology that requires no prior knowledge of genome sequence, and is therefore potentially useful in non-model and genetically uncharacterized organisms.

Genomic association approaches readily translate to non-model systems, and genetically explicit climate envelope models will predict future species' distributions under changing climates.

There are numerous mouse models available for HCC research, which can be broadly divided into (1) xenograft models, (2) chemically induced models and (3) genetically modified mouse models [ 45].

Our mouse breast cancer model morphologically and genetically resembles the osteoclastic bone microenvironment observed in human disease.