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Nurses are teachers, advocates, counsellors, role models and clinical experts.
Various types of cell sheet transplantation have improved cardiac function in animal models and clinical settings.
Animal models and clinical studies established the involvement of glutamate and GABA neurotransmission in drug addiction.
Discrepancies between experimental pain models and clinical studies including chronic pain patients are usually reported in the literature.
Not surprisingly, MSCs are currently tested in various animal models and clinical trials for lung and brain regeneration [103 105].
Combinations of BH3-mimetics with anti-tumor drugs are being evaluated in both preclinical models and clinical trials.
Drug disease models and clinical trial simulations are increasingly being used to support trial design and treatment optimization decisions.
Several potential cytokines have been proven to induce enhanced immune responses in animal models and clinical tests.
Translational models and clinical trials have highlighted both the immense challenges involved and some striking examples of success.
Here we aim to provide a translational overview of cytokine inhibiting therapies tested in experimental models and clinical studies.
The best form of combination therapy that leads to improved survival in patients remains to be seen in future by mathematical models and clinical trials.
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