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The four sets of 100 datasets simulated with empirically estimated substitution models and branch lengths on the 27-taxon salamander phylogeny produced variably inaccurate, but generally poor, estimates of branch length.
POTION currently supports three popular nested models implemented in codeml (M1a/M2; M7/M8 and/or M8a/M8), and future versions will include other models and branch- and branch-site analyses.
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Table 3 lists the log likelihood values and parameter estimates for the C-terminal domain of PCSK9 under several site models and branch-site models.
To examine the selective pressure acting on the pika leptin gene, three codon substitution models of maximum likelihood analysis were performed: branch-specific likelihood models, site-specific likelihood models, and branch-site likelihood models.
We used both site models and branch-site models to detect positive selection.
Three approaches were employed: branch models, site models and branch-site models with the use of the PAML package.
We applied the different codon substitution models implemented in codeml (Branch Models, Site Models and Branch-Site Models).
We analyzed the site models and branch-site models on the large and small datasets with likelihood ratio tests (LRT), respectively.
The positively selected sites found by site models and branch-site models were located on the SMase D three-dimensional structure (see below).
According to different studies [ 19– 24, 34], our first approach to address this problem consisted in the analysis of branch models, site models, and branch-site models.
Site models and branch-site models in PAML [ 61] were used to detect positive selection in the WRKY gene family of soybean.
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