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Gamma-secretase inhibitors have also shown positive results in laboratory animal models and, administered in low doses, they are safe in humans and reduce plasma Aβ [ 54].
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For the PTZ-induced model, compounds were prepared in the same way as those in the MES-induced model and administered to male KM mice by intraperitoneal injection in a volume of 0.2 ml/10 g 30 min before administration of 100 mg/kg PTZ sc.
Huettermann et al. (2014), for example, examined the effect of leadership on team identification of UN Peace-building team members and found four dimensions of leadership that positively affect team identification: providing guidance, encouraging involvement, role modeling, and administering teamwork.
To measure writer's idea generation process while composing, a Likert Scale questionnaire based on Chenoweth and Hayes 2001 and 2003 models was designed and administered to the students after their diagnostic essay task.
OVA and the mucosal adjuvant CTB were used as a model vaccine formulation and administered by the nasal route to study T-cell priming.
Founded nine years ago, it was an early mover in the franchising model, raising and administering its own funds, while remaining connected to the original DFJ by way of the DFJ Network.
To challenge their hypothesis, the authors have used their mt-Deletor mouse, a model of mitochondrial myopathy, and administered the NAD+ precursor, NR.
To confirm the neutralizing effect of MT95-4 APN/CD13APN/CD13 in vivo, we established a tail vein metastasis model and a subcutaneous xenograft model using APN-B16 cells and administered MT95-4 (1 mg/kg) i.p. twice per week in tumor-bearing mice.
To collect the data needed to estimate the model, a survey was designed and administered face-to-face in January 2015 in Xi'an, China using a random sampling procedure.
In contrast, the maximum plasma peak levels of EGCG in human and animal models administered with higher doses through drinking or diet is less than 10 μM [ 2, 35].
Other antibodies, Fab, peptides and growth factors have been shown to exert beneficial effects on animal models when administered within the therapeutic and safe window.
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