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These expressions are used to predict filter efficiency in 3 models: a direct deterministic model, a model that incorporates the statistical nature of particle movement, and a model that includes a measure of particles susceptibility to be maintained in suspension due to turbulent fluctuations within the flow.
The 6 state kinetic model presented in Figs. 1 and 2 fully accounts for experimental observations that have never been modeled over the full range of experimentally resolved time scales and with half the states of previous models (a direct comparison with the state of the art model can be found in the supplemental Fig. S1).
Predicted experimental outcomes are illustrated for two competing models: a direct TPP1 telomerase interaction and an interaction bridged by a yet-unidentified factor (BF?).
In murine vivo models, a direct demonstration of the tumourigenic and metastatic potential of this protein has been done (Garrido et al, 1998; Gibert et al, 2011).
Previous studies have shown ERα regulates its target genes through three major binding models a) direct binding to ERE (estrogen response element); b) indirect binding, through which it binds to other TF partners which bind to DNA; and c) co-occurrent binding, where both ERα and other TF partners bind to their own specific DNA motifs (Additional file 3, Figure S2) [ 20- 22, 40, 41].
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Using the obtained binormal mixture model a direct estimate of the true seroprevalence per age category was obtained, making correction for sensitivity and specificity unnecessary.
The results of the present study confirm the hierarchy predicted by the model: a direct comparison of activation for the detection of a contour-preserved versus a contour-violated difference revealed greater activation for processing contour-preserved differences.
Modeling a direct sclerostin signal on OPG production rate had the desired effect of rapidly decreasing the simulated CTx levels, immediately following a dose of sclerostin mAb.
Additionally, in at least one laboratory model, a direct thrombin inhibitor (dabigatran) has been shown to inhibit both invasion and metastasis of malignant breast cancer cells [ 69].
Larger inverters can handle bigger loads, but larger models need a direct connection to a car battery.
However, the development of general models without a direct relation to data is not deemed adequate for our journal.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com