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In the way of determination of parameters of different models a clear distinction should be made between two approaches: (i) parameter estimation (classical approach) and (ii) ANN approach with the aim of prediction (mainly interpolation).
In the case of QSAR models, a clear strength is the ability to make use of literally thousands of experimental results to both build and test the model, and to be able to select from the thousands of potential descriptions of the chemical substances those descriptors which most accurately correlate with the observed toxicity.
In each of the four Glyma models, a clear peak for the absolute number of tags is found at the predicted cleavage site for gma-miR159, gma-miR4406, gma-miR167, or gma-miR164.
Despite recent advances in identifying important subgroups of PSC and learning important aspects on their natural history as well as the increasing availability of animal models a clear and conclusive picture in regard to disease initiation and pathogenesis is still lacking.
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Before description of the model, a clear scope of the problem and set of assumptions were defined.
Therefore, independent of what happens within a specific model, a clear labeling of the inputs and outputs of the model is required.
"So far, the Android business model has meant that we haven't had to charge phone makers for our technology, or depend on a tightly controlled distribution model". A clear hint that things could change.
In the late stage of the GKO model, a clear hypoxic zone was found at the periphery of the necrotic regions.
In order to achieve a better liver model, a clear understanding of its structure is needed.
In a recent study, looking at fractionated intraperitoneal RIT in a murine gastric cancer tumour model, a clear therapeutic advantage was seen following fractionation.
However, although a significant proportion of GPs has voluntarily participated in some aspect of the model, a clear majority in the deanery has yet to do so.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com