Kaplan-Meier curves summarize 5-year OS and 3-year DFS by chemotherapy regimen and RDI, and multivariable Cox proportional hazards regression was used to model these associations.
Although each of the non-African ancestry components of the SAC (European, South Asian and East Asian) were negatively associated with TB susceptibility when tested in individual models, these associations were no longer significant when all five ancestry components were tested together.
In the initial model (Model 1), these associations were assessed with adjustment for age, sex, BMI, current smoking and daily drinking, the presence of antihypertensive medications, and eGFR.
In accordance with the uncertainty management model, these associations were dependent on experienced work-time control and perceived changes at work.
In the fully-adjusted model, these associations did not change markedly.
In the adjusted models, these associations remained negative but became non-significant (table 4).
In multivariable logistic regression models, these associations were adjusted for nationality, partner status, smoking, prenatal care, and BMI.
After controlling for variables included in our multivariate model, these associations remained significant (home tests: OR = 1.58 (1.01–2.53); PrEP: OR = 2.11 (1.2.11.47)).
For all models, these associations were independent of associations between obesity and systemic inflammation, which was also statistically significant for all models.
When pain was substituted for the presence of breast-related symptoms in the multivariate logistic regression model, these associations were stronger, but became less stable (data not presented).
