It is concerned with the development of new computational tools such as databases and modelling systems, but it also encompasses research into the similarities and differences between artificial and natural intelligence.
Escherichia coli finds extensive use as a model system, but has not been widely used as an industrial host.
We studied Bicoid because it was a well-characterized model system, but the applications are universal". Bialek has already used some of the team's results to sharpen new mathematical questions.
Birds are our most common model system, but we also have worked with insects, spiders, shrimp, lobsters, lizards, and primates, including humans.
Finally, we have now been awarded a NIH sponsored Mycology Unit for 5 years with 6 senior investigators which is focused on C. neoformans as a pathogenic model system, but will include multiple areas of medical mycology from diagnosis to treatment.
Therefore, signaling through the IFN-γ receptor may directly or indirectly influence IL-17A production in our model system, but is not entirely responsible for IL-17A production.
Therefore, some F. tularensis factors required for virulence in mammals are also required for virulence in the arthropod model system, but there are distinct molecular differences utilized by F. tularensis to exploit the two hosts [22], [23].
Disrupting microtubule organization eliminated such peripheral localization of DMs in this model system, but it did not affect their association with chromosomes, indicating that a microtubule-mediated antipolar force would be responsible for the mitotic fluctuation of DMs.
The presence of differential signature gene expression in in vivo data suggests that relative expression of oxygen-responsive genes is not simply a consequence of the adaptation of NZM tumour cells to culture in our model system, but is likely a snapshot of prevailing transcription at the time the tumour sample was removed.
Interestingly, preclinical evaluation of monoclonal antibody therapy with bevacizumab and/or cetuximab has not been conducted in a syngeneic model system, but rather in xenograft systems [ 28, 85].
