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The lithosphere-asthenosphere boundary beneath the study area (Figure 8b) has been derived from a 3D integrated geophysical modelling study by Gradmann et al. ([2013]), who used the lithospheric geometry from published data sets (Calcagnile [1982], Artemieva [2006], Ebbing et al. [2012]) with adjustments applied to the depth of the lithosphere in order to match seismic velocity constraints.
A computational modelling study by Hasselmo (Philos. Trans. R. Soc. Lond. B, Biol. Sci. 369 20120523, 2013) showed that an inhibitory network of such cells can support periodic travelling waves with a period that is controlled by the dynamics of the (I_{text{h}}) current.
The additional dependence of the branching probability on the within-branch position led us to propose an extension of a previous modelling study by Nowakowski and co-workers which could account for a large range of topological and metrical (length) dendritic tree structures.
For example, one influenza modelling study by Jones and Adida [ 22] assumed a fixed average cost for each infection.
In contrast, the independent economic evaluation commissioned by NICE [ 33], and the bevazicumab modelling study by Raftery and colleagues[ 28] assumed that after a two-year ranibizumab treatment period visual acuity would decline at the same rate as observed in the control group.
Interestingly, in line with the multifactorial nature of ALS, a recent modelling study by Al-Chalabi and colleagues suggests that in ALS, an underlying genetic susceptibility occurs in combination with environmental factors, which culminates in up to six exposures with the final exposure triggering the onset of disease [ 21].
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This is confirmed by modelling studies [ 104].
Modelling studies by ventilation engineers were then summarized to explain why these results were not unexpected.
The influenza modelling studies by Jones and Adida [ 22] focused on demonstrating the feasibility of the methods rather than reporting key economic results.
Modelling studies by Karami et al. (2011) indicate that the restricted exchange with the open ocean resulted in an increased sensitivity of the Paratethys to climate change and atmospheric forcing.
A recent model study by Wang et al.
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