Likewise, climate modelling studies suggest that the collapse of the LIS had a warming effect on E. Beringia33, although the dynamical response of summertime atmospheric circulation patterns in the North Pacific sector to LIS collapse is unknown.
Owing to the relatively small magnitude of the solar cycle amplitude (around 0.6 W m−2), modelling studies suggest that the effects are relatively small, but still clearly visible even at the surface owing to the relatively long period38,39.
This biophysical data, together with modelling studies, suggest that 2′,5′-linked α-L-ONA is a poor structural mimic of α-L-LNA.
Observational and modelling studies suggest that the recent multidecadal trend of rising sea surface temperatures (SST) in the North Atlantic's Main Development Region (MDR) may have increased Atlantic tropical cyclone (TC) intensity and duration1,2,3, and shifted storm tracks poleward4,5.
Molecular modelling studies suggest that these compounds might bind at the peripheral binding site of AChE, which opens the possibility to design inhibitors able to bind at both, the catalytic and peripheral binding sites of the enzyme.
Theory, common sense and modelling studies suggest that some interventions to mitigate greenhouse gas (GHG) emissions in the transport sector can, in addition to the long term benefits from stabilising the global climate, have substantial short term benefits for population health.
A recent meta-analysis, largely based on US modelling studies, suggested that for every 1% increase in price, energy intake would reduce by 0.02%.
The 6-position was chosen as a suitable point for appending this side-chain as modelling studies suggested that this region of the molecule was solvent exposed, so would be amenable to the introduction of this group.
Most of these modelling studies suggested that reducing animal-based products would reduce dietary GHG emissions (Baroni et al. 2007; Berners-Lee et al. 2012; Macdiarmid et al. 2012; Saxe et al. 2013), but one scenario considered by Vieux et al. (2012) suggested that reduced meat diets may increase dietary GHG emissions.
However, as the results of this modelling study suggest, the required dimensions of both reactor units may strongly differ from those expected on the grounds of a contaminant-specific design.
A modelling study suggests that the ecology of host co-colonisation may play a key role in shaping population-level frequencies of antibiotic resistance in commensal bacteria.
