Sentence examples for modelling proteins with from inspiring English sources

The notion behind this procedure is that protein structure is more conserved than sequence through evolution, a very general concept that helps in modelling proteins with similar sequences as long as their sequence identity (SI) is ≥30% over the alignment length (9, 10).

Using PhyloBayes and modelling protein evolution with the CAT model [ 32], Xenoturbella is still recovered as a basal deuterostome, but with low support (61 pp) and the urochordates are recovered as deuterostomes with high support (95 pp), even if within paraphyletic echinoderms, rather than with the chordates.

Biasini, M. et al. SWISS-MODEL: modelling protein tertiary and quaternary structure using evolutionary information.

Biasini M, Bienert S, Waterhouse A et al. SWISS-MODEL: Modelling protein tertiary and quaternary structure using evolutionary information.

Other practical consequences are related to the possibility of modelling protein interactions, engineering specific interactions and designing molecules to interfere with the protein protein recognition process (i.e., in signalling pathways), which would certainly benefit from a more precise understanding of the potential physical co-adaptation between proteins in protein complexes.

Several potential energy functions have been used in modelling protein structures [27], [37], [38].

We anticipate that BindN+ can provide a useful tool for modelling protein-nucleic acid interactions in systems biology studies.

Manual annotation and homology modelling analysis revealed that HADO encodes a haloacid dehalogenase (HAD) domain protein with structural similarity to the human magnesium-dependent phosphatase Mdp-1 (Supporting Information Fig. S5; Seifried et al., 2013).

Previous modelling studies have showed that the SNP at site 4257G>A occurs in a site crucial for ligand-receptor interactions resulting in an IL-13 protein with enhanced binding affinity for its receptor [ 26].

Eat protein with carbohydrates.

Replace fatty protein with lean protein.