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These modelling procedures were then carried out independently (25 models) for each state to examine the anaemia trends for each state.
Computer programs identified each subject's ten most representative cycles, and multilevel modelling procedures were used to estimate variances.
The modelling procedures were validated firstly through comparison with existing test data and secondly through the testing and analysis of representative structures.
The same modelling procedures were used for the modelling 'long-term' HRM (none versus one or more long-term HRM).
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Therefore numerical and modelling procedures are essential.
The modelling procedures are all twofold; consisting of a solution to a steady-state heat conduction problem followed by a linear static solution.
With the ultimate aim of developing a Crop Design Tool that will specify resource-efficient ideotypes for any environment, modelling procedures are proposed and tested here whereby wheat phenology can be optimised according to risks of abiotic damage (frost, heat and drought) to seedling establishment and grain set.
These modelling procedures are generally only a little more difficult than for single-event data, and software is widely available.
Hence, a general limitation of in silico drug-target interaction and activity modelling procedures is their inability to mimic entire cellular processes.
With the growing amount of available high resolution membrane protein structures (Garman, 2014; White, 2004) the template situation for homology modelling procedures is improving quickly and, even more important for this work, it is gradually becoming possible to adapt knowledge-based methods to this class of models.
However, despite the possibility of a discrepancy in its absolute level, it seems probable that our conclusion about the decrease in the expected rate of population decline is reliable, because the same assumptions and modelling procedure were used for all three survey periods.
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