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However, these models have never been used to calculate the dual-input for kinetic modelling of liver physiology.
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Therefore, the impact of MSCs on portal hypertension and fibrosis should be investigated in an animal model of liver cirrhosis.
In vitro models of liver physiology have been developed and new technologies and approaches are progressing rapidly.
They have been also used in preclinical models of liver necrosis and myocardial infarction as well as in clinical correlates of these pathophysiologic states [46, 47].
Accordingly, treatment with nanoscale photosensitizers resulted in improved outcomes (tumor volume) in a mouse model of liver cancer, in comparison with conventional photosensitizers.
The few reported experimental models of liver trauma use the "clamp and crush" mechanism of injury and do not cause reproducible liver injury.
When constructing an in vitro model of liver tissue to mimic the in vivo liver microenvironment, the major challenge is to preserve and maintain the hepatocyte phenotype.
This review discusses existing in vitro and animal models of liver metastasis, which are unique and practical models for investigating the mechanisms underlying tissue-specific metastasis.
This study was designed to further analyze the molecular mechanisms underlying the protective role of IL-6 in a rat model of liver ischemia/reperfusion injury.
In this study we determined the pharmacokinetics and target specificity of M6P-HSA-liposomes in a rat model of liver fibrosis.
To investigate the safety and effectiveness of a novel endovascular approach for therapeutic cell delivery using a balloon occlusion catheter in a large animal model of liver fibrosis.
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