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Despite this strong relationship, the present data did not support a single-factor modelling of Depression and Anxiety.
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A recent study by Will et al found that selectively bred WKY rats were a particularly good animal model of depression and hyper-responsiveness to anti-depressants [ 13].
Our previous studies have demonstrated that XCHT improved depressive-like behavior in several animal models of depression.
In animal models of depression, administration of leptin has been shown to improve depressive behaviors and exert antidepressant-like effects [ 10, 11].
Restoration of body weight by antidepressant treatment, particularly citalopram, in animal models of depression has been shown to to accompany recovery from a depressive-like state [ 130].
I used to be convinced by the biomedical model of depression, but now I'm not so sure.
Olfactory bulbectomy (OBX) model has been proposed as a well documented model of depression.
This study used a mixed-method design to explore older Hispanics' explanatory model of depression.
The results replicate previous studies and provide further support for a metacognitive model of depression.
In conclusion, these various findings reiterated the antidepressant-like effects of'6n' in behavioral models of depression.
The antidepressant-like effect was estimated using the rat olfactory bulbectomy model of depression.
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