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Much of the supporting data for this hypothesis has originated from studies using in vitro cultured cells or brain slices, or in vivo modelling of acute inflammatory responses using agents such as LPS (lipopolysaccharide) (Klegeris et al., 1994; Hu et al., 1995; Meda et al., 1999; Colton et al., 2000; Lee et al., 2002; Block and Hong, 2005; Bernardino et al., 2008).
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This model of acute inflammation is biphasic.
The pharmacological inhibition of TREM-1 confers protection in several pre-clinical models of acute inflammation.
To assess the effects of local heparin treatment in a rat model of acute lung injury.
Experimental models of acute lung injury with ECMO are usually too short.
An animal model of acute peri-implant osteomyelitis was modified for this study.
NETs have also been associated with tissue damage in experimental models of acute lung injury.
3. Proudfoot AG, McAuley DF, Griffiths MJ, Hind M. Human models of acute lung injury.
We used separate mouse models of acute myocardial ischemia-reperfusion injury and renal ischemia-reperfusion injury.
Thioacetamide (TAA) has been used in development of animal models of acute hepatic encephalopathy (AHE).
Additionally, efficacy in mouse and rat models of acute and chronic inflammation was obtained.
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