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This is likely to be important in large modelling initiatives like the Physiome project (physiomeproject.org), since compact cell models can be more confidently and effectively applied as parts of large multi-scale whole organ models.
Consequently, we further detail how both experimental interrogations and modelling developments can be utilised to investigate and reduce such difficulties before summarising how cartilage modelling initiatives may improve our understanding of cartilage ageing, pathology and intervention.
A direct measure of neutralising antibodies to 2009 H1N1 before and after the first wave provides the cumulative incidence estimates of asymptomatic and symptomatic infections in a population, which could inform modelling initiatives for predicting subsequent pandemic waves [6].
However, modelling initiatives have projected increasing numbers of HCC deaths attributable to hepatitis B and/or hepatitis C virus (HCV) infection (Deuffic-Burban et al, 2004, 2007; Sweeting et al, 2007).
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The most recent coordinated regional climate modelling initiative, CORDEX, provides RCM data for Europe with increased spatial resolution (12.5 km for the CORDEX EUR-11 ensemble) and based on the new Representative Concentration Pathways (RCPs).
As an outcome of this modelling-based initiative, managing agencies have revised previously drafted payment schemes and reconsidered the importance of monitoring and regulatory approaches.
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This article provides an overview of several modelling studies which demonstrate that well-designed initiatives that curb greenhouse gas emissions in energy, residential construction, urban transport and agricultural systems can enhance global public health, including improving health among poor populations.
Within a random utility maximisation modelling framework, the paper develops a residential location choice model as part of an integrated transport and land use modelling system, called MetroScan – a quick scanning tool to evaluate transport and land use initiatives, including benefit-cost analysis and economic impact analysis.
It's a major EU-funded inithative that will pull together all the latest science, initiate a fair few laboratory experiments and new modelling work, and then try to come to some definitive positions.
Our review also included studies published in 2010, yet since no initiative to improve the quality of reporting of prediction modelling studies has been put in place, we feel, that whilst methodology may have evolved there is no belief that reporting will have improved.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com