Recent studies have reported on the use of multiplexed cytokine analysis coupled with multivariate regression modeling in mouse models of inflammation, e.g. colitis [34], [35].
The degree to which all aspects of JBTS have or even can be modelled in mouse is difficult to assess.
Features of alcoholism, such as alcohol dependence, tolerance, and impaired control over alcohol drinking have been successfully modeled in mice.
In this study, the impact of individual MHC class I alleles on the Ly49 receptor repertoire was tested and modelled in mice with single MHC class I alleles.
These assays will be suitable to assist in the characterization of cancer and other diseases modeled in mice that are associated with altered expression of cystatin genes.
These results confirm that CCDS1 can be well modeled in mice.
Human GBM was modelled in mice by intracranial implantation of U87MG.EGFRvIII cells.
Laparoscopic insufflation was modeled in mice along with anesthesia and ventilation.
Prion disease is modelled in mice through ME7 prion agent infection resulting in both a behavioural phenotype and synaptopathy [ 44].
A benign neoplasia resembling hemangioma was also modeled in mice xenografted with HUVECs expressing polyoma virus middle T antigen.
