Although bioinformatics and modelling have contributed considerably to the functional assignment of proteins, significant portions of sequenced genomes (between 30 and 40% of genes by a recent estimate 1) remain unannotated or are ascribed a putative function.
Last, it makes the case that the contemporary de-contextualization of Hubbert's model has contributed towards a narrow focus of discussions within the oil industry and in certain governments on predicting the timing of a global peak, without addressing the wider questions implied by Hubbert's model.
A little later, looking back at Facebook's different tests with advertising, faberNovel makes a good argument for how a lack of success with more traditional models has contributed to it being such an innovative company.
Since 2009, Let Girls Lead's externally validated model has contributed to improved health, education, livelihoods, and rights for more than 3 million girls through laws, programs, and funding.
It is certainly not lost on people in Southeast Asia, that the WTO's corporate trade model has contributed to global inequality, wherein some consume far more than their share of resources, resulting in climate change - while others still struggle to feed their families, and suffer the impacts of extreme weather events like Typhoon Haiyan.
The model has contributed to the discovery of novel mechanisms regulating behavioral responses to stress, but its utility has been largely limited to males.
Thus, research on this animal model has contributed to important progress in neuroscience, development, signal transduction, cell death, aging, and RNA interference (http://www.wormbook.org).org
Studying the function of this highly conserved transcription factor in animal models has contributed to understanding its molecular function.
The generation of Nf2-mutant mouse models has contributed important information regarding Merlin function in development and tumourigenesis.
Despite considerable medical and economic burdens, delirium is poorly understood, and a lack of animal models has contributed to this.
