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Hence, this modelling framework represents a combined parameter fitting and systematic analysis of model behaviour and model mechanisms for possible model reduction.
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As all mathematical modeling approaches, our framework represents an abstraction of the biological system and as such should be considered as a toy model to investigate several characteristics of the system.
To perform such an analysis, classes from several biomedical ontologies can be employed, depending on the modelling framework and the kind of phenomena that the models in this framework represent.
Realistic assessment of scenario impacts often requires complex integrated modelling frameworks that represent environmental and socioeconomic systems to the best of our knowledge, including assumptions about plausible future conditions.
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