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Modelling experiments suggest that these differences could be explained by the electrostatic properties of the Cu+ releasing cavities of the two transporters and/or by the different nature of their cognate Cu+ acceptors (metallochaperone/PC).
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These results are in agreement with molecular modelling experiments suggesting that the free energies of the furanoid aldoses serving as starting materials are generally slightly higher than the values for the corresponding open-chain ketose.
These modelling experiments suggested that each protein pair could potentially interact in two distinct orientations, which involved mainly hydrophobic interactions between the α2/α5 surface (the aforementioned hydrophobic patch) in one DED and α1/α4 surface of the adjacent DED.
Modelling experiments also suggest that interactive effects between climate and CO2 are important, especially for predicting leaf area index (LAI) and ET in grassland catchments or runoff in water-limited catchments, where interactive effects were 1 6%.
As observed in previous modelling studies, our centrifuge experiments suggest that the angle of offset between the master fault segments is one of the most important parameters controlling the architecture of pull-apart basins: the basins are lozenge shaped in the case of underlapping master faults, lazy-Z shaped in case of neutral offset and rhomboidal shaped for overlapping master faults.
Other experiments suggest the same thing.
For all niche modelling experiments, we specified 200 models with a maximum of 1,000 iterations and a convergence limit of 0.01.
L.J.W. performed all model building, refinement, structural analysis and modelling experiments.
Our experiments and modelling results suggest a distinct role for two antioxidant mechanisms during stomatal closure: a slower, delayed response activated by a single stimulus (abscisic acid 'or' ethylene) and another more rapid 'and' mechanism that is only activated when both stimuli are present.
S.N.G. coordinated impact modelling experiments.
J.L.R. performed the firn modelling experiments and interpretation.
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