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Phylodynamic approaches are increasingly being used to obtain estimates of sequence evolution rates and epidemic network parameters [ 24], with mathematical modelling demonstrating that inter-subtype recombination has clearly been a substantial force in generating HIV-1 group M diversity [ 25].
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Hierarchical linear modeling demonstrated that skills practice increased as a function of time in therapy.
Modelling demonstrates that this sequence of evolutionary events requires a strong selection pressure.
Moreover, our modelling demonstrates that both the viral load and CD4+ T cell data are consistent with a non-cytolytic model.
Regression modelling demonstrated that Attitude scores were a positive predictor of Practice scores.
Multivariate but not univariate modelling demonstrated that IV patients with aberrant vs normal BRCA1 expression had worse survival.
The PK-PD modelling demonstrated that VI exposure (Cmax) was related to increases in both heart rate and QTcF.
Another recent study has linked LRH-1 with ovulation in a rodent model, demonstrating that this receptor is required for rodent ovarian follicular development and fertility [17].
There are several studies in animal models demonstrating that stromal cells not only seed the bone marrow but also enhance hematopoietic recovery [34], [35].
We now have new data from newly developed mouse models demonstrating that MELK is not essential for normal physiological functions.
Computer models demonstrated that meltdowns were very unlikely.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com