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Heterogeneity in the population was tested in the model through the sensitivity analysis, but future modelling could simulate individual patients with different characteristics and link these to treatment effect if clinical trial data allowed.
Decision modelling could simulate the medicines pathway in a specific disease and integrate formal evidence, such as from RCTs or previous systematic reviews, complemented with input from experts in the form of expert elicitation to address the evidence gaps.
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This model could simulate a multicomponent gas mixture separation by solving the governing differential mass balance equations with numerical methods.
As a next step, co-cultured mini-organ models could simulate pharmacokinetics and pharmacodynamics in physiological and pathological conditions.
Phase mixture modeling could simulate the absence of strain hardening associated with the grain boundary mediated plastic deformation mechanism.
Realizing that Dr. Tonge's model could simulate asteroid impact events, the team merged it with another model that also replicated the effects of a large asteroid's gravitational field.
It is demonstrated that the present MECis model could simulate well the responsive behavior of the ionic-strength-sensitive hydrogel quantitatively.
The current investigation demonstrates that the proposed hybrid model could simulate the refrigerant flow in parallel flow condensers efficiently and its prediction has a reasonable precision.
A closed loop simulation demonstrated that an operator model could simulate the trenching work cycle with multiple operator strategies, and adapt to different vehicle and work site settings.
The micromechanical model could simulate the matrix failure and debonding of the fiber/matrix interface by the Christensen failure criterion and cohesive zone modeling, respectively.
Furthermore, the finite element (FE) models of BRBs with various gusset connections were established and good consistency between the numerical and test results indicated that the FE modeling could simulate the cyclic behavior of BRB well.
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