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In this model, the drug delivery is mimicked, in a manner similar to Wilensky (1999), we have introduced the durg into the agent based modelling, by targeting the transitory cells.
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In our case, we used caret package in R, which constructs a linear model by targeting a dependent attribute against the number of input attributes and then ranking with respect to their estimated importance.
This suggests that city authorities may develop effective AQ models by targeting their investment in AQ monitoring to the parameters of interest, a vast feature space not being necessary for the success of the modelling approach.
We have generated a lung cancer mouse model by targeting constitutively active C-Raf kinase to the lung.
Previously BT was shown to inhibit solid tumor growth in several preclinical cancer models by targeting ATX [ 12, 13].
Most recently, two models have shed light on Shh-independent MB mouse models by targeting different cell populations during CNS development.
Previously, we had generated a lung cancer mouse model by targeting constitutively active C-Raf kinase (SP-C C-Raf BxB) to the lung [ 14].
Sorafenib has also been shown to inhibit the growth of several human tumour xenograft models by targeting tumour cell proliferation and/or endothelial cell-mediated tumour angiogenesis (Wilhelm et al, 2004).
Sorafenib blocks tumor cell proliferation and tumor angiogenesis, and increases the rate of apoptosis in a wide range of tumor models by targeting the Raf/MAPK- and VEGF-mediated pathways.
To investigate the effects of deregulated expression, we generated a novel transgenic model by targeting Runx2 to mammary epithelium using the mouse mammary tumour virus (MMTV) promoter (MMTV- Runx2).
Finally, we studied the effect of BT on ATX secretion in ovarian cancer cell lines because BT has been shown to inhibit solid tumor growth in several preclinical cancer models by targeting autotaxin [ 12, 13].
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