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PK modelling, as one of the elements identifying the key properties of a drug, plays an increasingly important role in drug development combining with the druglikeness evaluation.
Schultze (1995) describes the problem of hydrological modelling as one of "dealing with a system characterized by large temporal and spatial fluctuations, irregularities and discrepancies which occur more or less regularly through a series of dynamic, non-linearly lagged responses with feedback between elements of the system".
Exemplified by Reduning injection, a Chinese medicinal preparation consists of three herbs mainly treating influenza-related diseases, our main findings are: PK modelling, as one of the elements identifying the key properties of a drug, plays an increasingly important role in drug development combining with the druglikeness evaluation.
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The moving vehicle is modeled as one degree of freedom.
This paper explores landscape permeability modeling as one such geospatial approach.
Each particle is scattered stochastically from all the other particles in a simulation cell modeled as one or more Maxwellians.
We propose that this response can be modeled as one parameter that changes from one value to other in a smooth way.
Crosses indicate the cumulative slip shown in Fig. 2. Thus, the entire seismogenic zone is modeled as one large hyper asperity.
The problem can now be modeled as one of scheduling independent tasks of unequal load to processors of unequal computational power.
This finding suggests an asymmetric disturbance caused by a localized pre-midnight SCW in addition to the broader disturbance modeled as one SCW (Fig. 1d; Additional file 1: S1).
The prior is modeled as one multivariate normal distribution N ( Ī, R I ) having the mean and covariance of the clean samples.
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