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Based on these experimental, modelling and theoretical results, guidelines are formulated to optimise the design of vertical borehole fields with an objective of inter-seasonal heat storage.
The overall importance of such individual differences for group outcomes are likely to be considerable, therefore future modelling and theoretical efforts may benefit from a better understanding of the nature and extent of individual variation in animal groups.
This is especially true in the field of carcinogenesis, where both experimental modelling and theoretical framework have been for a long time dominated by the SMT [ 14, 15].
Comparing to this new term, systems biology emphasizes the integration of experimental and computational research to understand the complex biological systems, while computational biology highlights the pragmatic modelling and theoretical exploration to address critical biological questions [ 2- 5].
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At report, we presented a common design and theoretical modelling scheme for a porous scaffold from nitinol with a shape memory effect (SME), fabricated by the selective laser sintering (SLS) process.
The first intervention of this nature took place 8 years ago and the patients involved have suffered no relapses so far, providing proof of concept of the approach (Haissaguerre, 2002b; Knecht, 2009) However, the impossibility of creating more elaborate maps forces us to rely on experimental and theoretical modelling studies of this lethal condition.
We also tested whether evolutionary journals publish high percentages of studies using modelling and conversely that theoretical-oriented journals publish high percentages of studies dealing with evolution.
Albeit the long record of the study on SSWs, the coupling processes between the stratosphere and the MLT are still not clearly understood, thus in needs of further advanced observations and theoretical modellings.
We are undertaking further SAR studies on our cis-Apc-substituted peptides using NMR and theoretical molecular modelling methods to provide structural rationale for the activity results.
The process involves stages of development – currently lacking in implementation research – that closely correspond to the theoretical, modelling and experimental phases of the MRC Framework for the evaluation of complex interventions [ 12].
We aimed to address this gap in the current evidence-base through the development of a systematic intervention modelling process (IMP) for intervention development and evaluation that corresponds to each of the theoretical, modelling and experimental phases of the MRC Framework [ 14].
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