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We modelled this effect in a phenomenologic way by multiplying toxicity parameters with a factor ≥ 1 at time of first application of chemotherapy.
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To investigate this point further we used an alternative approach involving the transfer function that modelled the effect of the most recent stimulus having allowed for the effect of earlier stimuli on the evoked activity in each subject.
We modelled these effects using population data from the UK for both sexes across different age groups to analyse benefits and harms of prophylactic aspirin use in the average-risk general population in the developed world.
The effect of sex was identical on the three events, men having poorer prognoses than women and this effect was advantageously modelled using our model with a (single) common parameter rather than three.
Because we modelled log(BMI), the modelled effect of each allele is reported as a percentage change (increase or decrease) in BMI.
In the ideal scenario, where immunity is allowed to build up during treatment as efficiently as if the individual goes through a full length of infection (c = 1), and the risk of infection is not reduced by treatment (σ = 1), the modelled rebound effect is minimised.
We modelled treatment effect using data from three clinical trials for nalmefene (ESENSE 1 (NCT00811720), ESENSE 2 (NCT00812461) and SENSE (NCT00811941)).
Since no tissue-specific effect can be assigned to experiments provided in [ 33], we considered whole brain average value R a l l T as a modelled knockout effect for comparison.
There was weak evidence of a reduction in overall life years lived with depression, which was consequent on the reduction in morbidity as there was no modelled direct effect of intervention on depression prevalence.
Standard random effects models assume that the modelled random effects are uncorrelated.
Figure 4 The modelled effect of most influential, significant anthropogenic (a, b, and c), climatic (d and e) and edaphic (f) variables of aboveground live carbon storage.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com